The solubility of ofloxacin in 1,2-dichloromethane, chloroform, carbon tetrachloride, and water was measured by a gravimetrical method from (293.15 to 313.15) K under atmospheric pressure, and the solubility data were correlated against temperature. The solubility is at a minimum in water and a maximum in chloroform. Further, some thermodynamic parameters such as enthalpy, Gibbs energy, and entropy for dissolution have also been evaluated. For 1,2-dichloromethane and chloroform, enthalpy, Gibbs energy, and entropy values are very close and lower than those for carbon tetrachloride and water.
Compounds
#
Formula
Name
1
C18H20FN3O4
ofloxacin
2
H2O
water
3
CH2Cl2
dichloromethane
4
CHCl3
trichloromethane
5
CCl4
tetrachloromethane
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.