Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Captopril in 2-Propanol, Acetone, Acetonitrile, Methyl Acetate, Ethyl Acetate, and Butyl Acetate

Wang, J.[Jingkang], Gao, L.[Li], Liu, Y.[Yan]
J. Chem. Eng. Data 2010, 55, 2, 966-967
ABSTRACT
The solubility of captopril in 2-propanol, acetone, acetonitrile, methyl acetate, ethyl acetate, and butyl acetate was measured by a synthetic method over the temperature range of (278.15 to 313.15) K at atmosphere pressure. The results show that the solubility of captopril increases with increasing temperature. The experimental data were correlated with the van t Hoff equation, and the agreement was very good.
Compounds
# Formula Name
1 C9H15NO3S 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-L-proline
2 C3H8O propan-2-ol
3 C3H6O acetone
4 C2H3N acetonitrile
5 C3H6O2 methyl ethanoate
6 C4H8O2 ethyl acetate
7 C6H12O2 butyl ethanoate
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser Monitoring Technique
  • 8
  • POMD
  • 3
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser Monitoring Technique
  • 8
  • POMD
  • 4
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser Monitoring Technique
  • 8
  • POMD
  • 5
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser Monitoring Technique
  • 8
  • POMD
  • 6
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser Monitoring Technique
  • 8
  • POMD
  • 7
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser Monitoring Technique
  • 8