ABSTRACT

The solubilities of penicillin sulfoxide in ethyl acetate, 4-methyl-2-pentanone, butyl acetate, and toluene from (273.15 to 332.75) K were measured with the mole fraction by a gravimetric method The solubilities in these solvents are temperature dependent. The results show that the solubility of penicillin sulfoxide in toluene is very low, so toluene is considered as one of the best solvents and used in industry. According to the results, we can see that the solubilities of penicillin sulfoxide in ethyl acetate, 4-methyl-2-pentanone, butyl acetate, and toluene can be correlated well with a semiempirical equation.

Compounds

#	Formula	Name
1	C16H18N2O5S	4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-, 4-oxide, stereoisomer
2	C4H8O2	ethyl acetate
3	C6H12O	4-methylpentan-2-one
4	C6H12O2	butyl ethanoate
5	C7H8	toluene

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1	Normal melting temperature, K ; Crystal			Crystal Liquid Air at 1 atmosphere	DTA	1
POMD	2 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Titration method	11
POMD	3 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Titration method	11
POMD	4 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Titration method	10
POMD	5 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Titration method	8

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Penicillin Sulfoxide in Different Solvents

Jing, D.[Dingding], Wang, J.[Jingkang], Wang, Y.[Yongli]

ABSTRACT