The characterizations of the ternary phase diagram and the metastable zone width are important issues for enantioseparation by crystallization procedures. In this work, a systematic study of the solubility and metastable zone width data of L-methionine, DL-methionine, and different mixtures of the enantiomers in water as solvent was performed. The eutectic composition in the chiral system in the presence of the solvent as an important characteristic for enantioselective crystallization was determined in the temperature range between (1 and 60) deg C. A significant shift of this composition was observed.
Compounds
#
Formula
Name
1
C5H11NO2S
L-methionine
2
C5H11NO2S
DL-2-amino-4-(methylthio)butanoic acid
3
H2O
water
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.