Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Valsartan in Ethyl Acetate + Hexane Binary Mixtures from (278.15 to 313.15) K

Liu, Y.[Yan], Wang, J.[Jingkang], Wang, X.[Xiaobo], Pang, F.[Fei]
J. Chem. Eng. Data 2009, 54, 4, 1412-1414
ABSTRACT
The solubility of valsartan in ethyl acetate + hexane binary mixtures was measured by a synthetic method over the temperature range from (278.15 to 313.15) K at atmosphere pressure. The results show that the solubility of valsartan increases with increasing temperature and the increasing mole fraction of ethyl acetate of the binary mixtures. The experimental data were correlated using the modified Apelblat model, and the agreement with the experimental data was very good.
Compounds
# Formula Name
1 C24H29N5O3 valsartan
2 C4H8O2 ethyl acetate
3 C6H14 hexane
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Synthetic Method
  • 8
  • POMD
  • 3
  • 2
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 2; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Synthetic Method
  • 80