Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Form B Pravastatin Sodium in (Water + 2-Propanol)

Jia, C.-Y.[Chun-Yan], Yin, Q.-X.[Qiu-Xiang], Gong, J.-B.[Jun-Bo], Wang, J.-K.[Jing-Kang]
J. Chem. Eng. Data 2009, 54, 7, 2120-2122
ABSTRACT
The solubilities of pravastatin sodium of form B in (water + 2-propanol) from (278 to 323) K were measured. A laser-monitoring observation technique was used to determine the dissolution of the solid phase in the solid + liquid mixtures. The experimental data were correlated with a semiempirical equation.
Compounds
# Formula Name
1 C23H35NaO7 pravastatin sodium
2 H2O water
3 C3H8O propan-2-ol
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 3
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser monitoring system
  • 10
  • POMD
  • 3
  • 2
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 2; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser monitoring system
  • 60