Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of (+)-(S)-2-(6-Methoxynaphthalen-2-yl) Propanoic Acid in Acetone, Methanol, Ethanol, Propan-2-ol, and Ethyl Ethanoate at Temperatures between (278 and 320) K

Yan, F.-Y.[Fan-Yong], Chen, L.[Li], Liu, D.-Q.[Dong-Qing], SiMa, L.-F.[Li-Feng], Chen, M.-J.[Min-Jie], Shi, H.[Heng], Zhu, J.-X.[Jin-Xin]
J. Chem. Eng. Data 2009, 54, 3, 1117-1119
ABSTRACT
The solubility of (+)-(S)-2-(6-methoxynaphthalen-2-yl) propanoic acid {otherwise commonly known as (S)-Naproxen} in pure methanol, ethanol, acetone, ethyl ethanoate, and propan-2-ol was measured at temperature ranging from (278 to 320) K at atmospheric pressure. A laser monitoring observation technique was used to determine the dissolution of the solid phase in a solid + liquid mixture. The experimental solubility data were correlated with a semiempirical Apelblat equation.
Compounds
# Formula Name
1 C14H14O3 (S)-(+)-naproxen
2 C3H6O acetone
3 CH4O methanol
4 C2H6O ethanol
5 C4H8O2 ethyl acetate
6 C3H8O propan-2-ol
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • Normal melting temperature, K ; Crystal
  • Crystal
  • Liquid
  • Air at 1 atmosphere
  • VISOBS
  • 1
  • POMD
  • 2
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laster monitoring observation technique
  • 10
  • POMD
  • 6
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laster monitoring observation technique
  • 10
  • POMD
  • 3
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laster monitoring observation technique
  • 10
  • POMD
  • 4
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laster monitoring observation technique
  • 10
  • POMD
  • 5
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laster monitoring observation technique
  • 10