Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Cloxacillin Sodium in Different Binary Solvents

Zhi, M.[Minjie], Wang, J.[Jingkang], Jia, C.-Y.[Chun-Yan], Wang, Y.[Yongli]
J. Chem. Eng. Data 2009, 54, 3, 1084-1086
ABSTRACT
The solubilities of cloxacillin sodium in binary butyl acetate + methanol and ethyl acetate + methanol solvent mixtures were measured at temperatures ranging from (283.15 to 298.15) K. The experimental data can be well correlated by the CNIBS/Redlich-Kister model. The results show that the solubility of cloxacillin sodium increases with increasing temperature and mole fraction of methanol in these two binary mixed solvents.
Compounds
# Formula Name
1 C6H12O2 butyl ethanoate
2 C4H8O2 ethyl acetate
3 CH4O methanol
4 C19H18ClN3O5S 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 4
  • 3
  • 1
  • Mole fraction - 4 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 3; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 4
  • laser monitoring system
  • 40
  • POMD
  • 4
  • 3
  • 2
  • Mole fraction - 4 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 3; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 4
  • laser monitoring
  • 40