Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Podophyllotoxin in Six Organic Solvents from (283.2 to 323.2) K

Gan, L.-S.[Li-She], Wang, Z.-Z.[Zhen-Zhen], Zhou, C.-X.[Chang-Xin]
J. Chem. Eng. Data 2009, 54, 1, 160-161
ABSTRACT
The solubility of podophyllotoxin (furo[3 ,4 :6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9- hydroxy-5-(3,4,5-trimethoxyphenyl), (5R,5aR,8aR,9R)) in ethanol, methanol, acetone, ethyl acetate, propan-2-ol, and butan-1-ol from (283.2 to 323.2) K was measured under atmospheric pressure. The solubility of podophyllotoxin in these solvents increases with increasing temperature. The solubility values were correlated with the Apelblat equation.
Compounds
# Formula Name
1 C22H22O8 podophyllotoxin
2 C2H6O ethanol
3 CH4O methanol
4 C3H6O acetone
5 C4H8O2 ethyl acetate
6 C3H8O propan-2-ol
7 C4H10O butan-1-ol
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • 1
  • Amount concentration (molarity), mol/dm3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • HPLC
  • 5
  • POMD
  • 3
  • 1
  • Amount concentration (molarity), mol/dm3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • HPLC
  • 5
  • POMD
  • 4
  • 1
  • Amount concentration (molarity), mol/dm3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • HPLC
  • 5
  • POMD
  • 5
  • 1
  • Amount concentration (molarity), mol/dm3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • HPLC
  • 5
  • POMD
  • 6
  • 1
  • Amount concentration (molarity), mol/dm3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • HPLC
  • 5
  • POMD
  • 7
  • 1
  • Amount concentration (molarity), mol/dm3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • HPLC
  • 5