Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Form A Pravastatin Sodium in Aqueous 2-Propanol Mixtures

Jia, C.-Y.[Chun-Yan], Yin, Q.-X.[Qiu-Xiang], Gong, J.-B.[Jun-Bo], Wang, J.-K.[Jing-Kang]
J. Chem. Eng. Data 2009, 54, 1, 154-156
ABSTRACT
The solubilities of pravastatin sodium of form A in aqueous 2-propanol mixtures from (278 to 323) K were measured. A laser monitoring observation technique was used to determine the dissolution of the solid phase in the solid + liquid mixtures. The experimental data were correlated with a semiempirical equation.
Compounds
# Formula Name
1 C23H35NaO7 pravastatin sodium
2 C3H8O propan-2-ol
3 H2O water
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • 3
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Mole fraction - 3; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser Monitering observation
  • 50