ABSTRACT

Enthalpies of solution of glycine, L-alanine, L-serine, L-threonine, diglycine, and triglycine in aqueous solutions of D-sorbitol, D-mannitol, and xylitol have been measured by calorimetry at 298.15 K. These data have been used to calculate the transfer enthalpies of the amino acids and glycine peptides from water to aqueous solutions of sugar alcohol. It has been observed that all the values of the transfer enthalpies are negative and decrease with an increase of the concentration of sugar alcohol in the aqueous solutions. The results are discussed in terms of solute-solute and solute-solvent interactions. The primary interactions between the zwitterionic group of the amino acid molecule and the hydroxyl group of the sugar alcohol molecule exhibit exothermic effects and make negative contributions to the transfer enthalpies. The hydrophilic side chains in the solute molecules also enhance these negative contributions effectively.

Compounds

#	Formula	Name
1	C2H5NO2	2-aminoacetic acid
2	C3H7NO2	(S)-2-aminopropanoic acid
3	C4H9NO3	L-threonine
4	C4H7NO4	N-(carboxymethyl)glycine
5	C6H9NO6	nitrilotriacetic acid
6	C6H14O6	D-sorbitol
7	C6H14O6	D-mannitol
8	C5H12O5	xylitol
9	H2O	water
10	C3H7NO3	L-serine

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1 9	Molar enthalpy of solution, kJ/mol ; Liquid	Mole fraction - 1; Liquid Pressure, kPa; Liquid Temperature, K; Liquid		Liquid	microcalorimeter	1
POMD	2 9	Molar enthalpy of solution, kJ/mol ; Liquid	Mole fraction - 2; Liquid Pressure, kPa; Liquid Temperature, K; Liquid		Liquid	microcalorimeter	1
POMD	10 9	Molar enthalpy of solution, kJ/mol ; Liquid	Mole fraction - 10; Liquid Pressure, kPa; Liquid Temperature, K; Liquid		Liquid	microcalorimeter	1
POMD	3 9	Molar enthalpy of solution, kJ/mol ; Liquid	Mole fraction - 3; Liquid Pressure, kPa; Liquid Temperature, K; Liquid		Liquid	microcalorimeter	1
POMD	4 9	Molar enthalpy of solution, kJ/mol ; Liquid	Mole fraction - 4; Liquid Pressure, kPa; Liquid Temperature, K; Liquid		Liquid	microcalorimeter	1
POMD	5 9	Molar enthalpy of solution, kJ/mol ; Liquid	Mole fraction - 5; Liquid Pressure, kPa; Liquid Temperature, K; Liquid		Liquid	microcalorimeter	1
POMD	6 1 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 6; Liquid	Mole fraction - 1; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	9
POMD	1 7 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 7; Liquid	Mole fraction - 1; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	1 8 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 8; Liquid	Mole fraction - 1; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	6 2 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 6; Liquid	Mole fraction - 2; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	2 7 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 7; Liquid	Mole fraction - 2; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	2 8 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 8; Liquid	Mole fraction - 2; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	6 10 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 6; Liquid	Mole fraction - 10; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	10 7 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 7; Liquid	Mole fraction - 10; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	10 8 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 8; Liquid	Mole fraction - 10; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	6 3 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 6; Liquid	Mole fraction - 3; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	7 3 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 7; Liquid	Mole fraction - 3; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	3 8 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 8; Liquid	Mole fraction - 3; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	6 4 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 6; Liquid	Mole fraction - 4; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	7 4 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 7; Liquid	Mole fraction - 4; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	8 4 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 8; Liquid	Mole fraction - 4; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	6 5 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 6; Liquid	Mole fraction - 5; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	7 5 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 7; Liquid	Mole fraction - 5; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8
POMD	8 5 9	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 8; Liquid	Mole fraction - 5; Liquid Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	microcalirimotry	8

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Transfer Enthalpies of Amino Acids and Glycine Peptides from Water to Aqueous Solutions of Sugar Alcohol at 298.15 K

Qiu, X.[Xiaomei], Lei, Q.[Qunfang], Fang, W.[Wenjun], Lin, R.[Ruisen]

ABSTRACT