Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Clindamycin Phosphate in Methanol, Ethanol, and Dimethyl Sulfoxide

Zhu, L.[Liang], Chen, Y.[Yi], Wang, J.-K.[Jing-Kang]
J. Chem. Eng. Data 2008, 53, 8, 1984-1985
ABSTRACT
The solubilities of clindamycin phosphate in different solvents (methanol, ethanol, and dimethyl sulfoxide) were measured at temperatures from (283.15 to 333.15) K by a synthetic method at atmospheric pressure. The experimental data were correlated with the modified Apelblat equation. The equation was found to provide an accurate representation of the experimental data. The dissolution enthalpy determined from the experimental solubility data was also presented.
Compounds
# Formula Name
1 CH4O methanol
2 C18H34ClN2O8PS clindamycin phosphate
3 C2H6O ethanol
4 C2H6OS dimethyl sulfoxide
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • Mole fraction - 2 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 2
  • Titration method
  • 8
  • POMD
  • 3
  • 2
  • Mole fraction - 2 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 2
  • Titration method
  • 8
  • POMD
  • 4
  • 2
  • Mole fraction - 2 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 2
  • Titration method
  • 8