The solubilities of pravastatin sodium in water, methanol, ethanol, 2-propanol, 1-propanol, and 1-butanol from (278 to 333) K were measured. A laser monitoring observation technique was used to determine the dissolution of the solid phase in the solid + liquid mixture. The experimental data were correlated with a semiempirical equation. The solubilities in the six solvents decrease in the following order: water greater than methanol greater than ethanol greater than 1-propanol greater than 1-butanol greater than 2-propanol.
Compounds
#
Formula
Name
1
C23H35NaO7
pravastatin sodium
2
H2O
water
3
CH4O
methanol
4
C2H6O
ethanol
5
C3H8O
propan-2-ol
6
C3H8O
propan-1-ol
7
C4H10O
butan-1-ol
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.