The solubility of pyridine-4-carbohydrazide (isoniazid) in ethanol, methanol, ethyl acetate, and acetone has been measured gravimetrically at various temperatures ranging from (301 to 313) K at atmospheric pressure. Isoniazid is most soluble in methanol, followed by acetone, ethanol, and ethyl acetate at a temperature up to 308 K. At higher than 308 K, isoniazid is most soluble in acetone. The experimental data were correlated using the modified Apelblat equation.
Compounds
#
Formula
Name
1
C6H7N3O
isonicotinic acid hydrazide
2
C2H6O
ethanol
3
CH4O
methanol
4
C4H8O2
ethyl acetate
5
C3H6O
acetone
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.