Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Lovastatin in Acetone + Water Solvent Mixtures

Sun, H.[Hua], Wang, J.[Jingkang]
J. Chem. Eng. Data 2008, 53, 6, 1335-1337
ABSTRACT
The solubilities of lovastatin in binary acetone + water solvent mixtures were determined by the synthetic method from (277.35 to 310.05) K by a laser monitoring observation technique. Results of these measurements were correlated by the semiempirical equation. For the nine mole fractions of acetone studied, a semiempirical equation was found to provide an accurate mathematical representation of the experimental data.
Compounds
# Formula Name
1 C3H6O acetone
2 C24H36O5 lovastatin
3 H2O water
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • Normal melting temperature, K ; Crystal
  • Crystal
  • Liquid
  • Air at 1 atmosphere
  • VISOBS
  • 1
  • POMD
  • 1
  • 3
  • 2
  • Mole fraction - 2 ; Liquid
  • Temperature, K; Liquid
  • Mole fraction - 1; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 2
  • laser monitoring observation technique
  • 90