Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of 6-Aminopenicillanic Acid in Aqueous Salt Solutions from 273.15 K to 303.15 K

Su, M.[Min], Wang, J.[Jingkang], Hou, Y.[Yan]
J. Chem. Eng. Data 2007, 52, 6, 2266-2268
ABSTRACT
The solubility of 6-aminopenicillanic acid in aqueous solutions of various concentrations of sodium sulfate and ammonium sulfate was determined from (274.15 to 303.15) K at atmospheric pressure using a synthetic method. Results showed that sodium sulfate has a salting-in effect on the solubility of 6-aminopenicillanic acid; ammonium sulfate has a salting-in effect if its concentration is below 0.5 M and a salting-out effect if its concentration is above 0.5 M. The solubility data were accurately correlated by a semiempirical equation.
Compounds
# Formula Name
1 C8H12N2O3S 6-aminopenicillanic acid
2 H2O water
3 Na2O4S sodium sulfate
4 H8N2O4S ammonium sulfate
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • 3
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Amount concentration (molarity), mol/dm3 - 3; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • laser monitoring
  • 35
  • POMD
  • 1
  • 2
  • 4
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Amount concentration (molarity), mol/dm3 - 4; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • laser monitoring
  • 31