ABSTRACT

The solubility of chlorpheniramine maleate in ethanol, 1-propanol, 1-butanol, benzene, ethyl acetate, ethyl formate, and butyl acetate was measured using a laser technique with the temperature range from 283 K to 333 K and at atmospheric pressure. The solubility of chlorpheniramine maleate in pure solvents increases with temperature and in the following order: alcohol solvents greater than ester solvents greater than benzene. The experimental solubility data were correlated with a semiempirical equation.

Compounds

#	Formula	Name
1	C20H23ClN2O4	chlorpheniramine maleate
2	C2H6O	ethanol
3	C3H8O	propan-1-ol
4	C4H10O	butan-1-ol
5	C3H6O2	ethyl methanoate
6	C4H8O2	ethyl acetate
7	C6H12O2	butyl ethanoate
8	C6H6	benzene

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	2 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	laser technique	11
POMD	3 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	laser technique	11
POMD	4 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	laser technique	11
POMD	5 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	laser technique	10
POMD	6 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	laser technique	11
POMD	7 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	laser technique	10
POMD	8 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	laser technique	11

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Chlorpheniramine Maleate in Ethanol, 1-Propanol, 1-Butanol, Benzene, Ethyl Acetate, Ethyl Formate, and Butyl Acetate between 283 K and 333 K

Li, Q.-S.[Qun-Sheng], Tian, Y.-M.[Yuan-Ming], Wang, S.[Shui]

ABSTRACT