Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of r-Tocopheryl Succinate in Supercritical Carbon Dioxide Using Offline HPLC-MS/MS Analysis

Hybertson, B. M.[Brooks M.]
J. Chem. Eng. Data 2007, 52, 3, 1123-1127
ABSTRACT
The solubility of the vitamin E-related compound R-tocopheryl succinate in supercritical carbon dioxide was measured at pressures ranging from (15.0 to 30.0) MPa and temperatures of (40 and 50) deg C using a simple microsampling type apparatus with a 100.5 iL sample loop to remove aliquots and collect them in ethanol for off line analysis. R-Tocopheryl succinate concentrations in the collected samples were measured using HPLCMS/ MS analysis. The solubility of R-tocopheryl succinate in supercritical carbon dioxide ranged from mole fractions of 0.28 10-5 at 15.0 MPa and 50 deg C to 2.56 10-5 at 30.0 MPa and 50 deg C.
Compounds
# Formula Name
1 C33H54O5 D-.alpha.-tocopheryl acid succinate
2 CO2 carbon dioxide
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Chromatography
  • 8