ABSTRACT

The solubilities of betulin in methanol, ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, methyl formate, ethyl formate, methyl acetate, ethyl acetate, chloroform, dichloromethane, cyclohexane, and acetone were measured at T= (278.2, 288.2, 298.2, and 308.2) K. The solubilities of betulin in selected organic solvents increase with temperature. A three-parameter equation was used to correlate the experimental data. These data of solubility can be used to guide the processes of crystallization in industry.

Compounds

#	Formula	Name
1	C30H50O2	betulin
2	CH4O	methanol
3	C2H6O	ethanol
4	C3H8O	propan-1-ol
5	C4H10O	butan-1-ol
6	C5H12O	pentan-1-ol
7	C6H14O	hexan-1-ol
8	C2H4O2	methyl methanoate
9	C3H6O2	ethyl methanoate
10	C3H6O2	methyl ethanoate
11	C4H8O2	ethyl acetate
12	CHCl3	trichloromethane
13	CH2Cl2	dichloromethane
14	C6H12	cyclohexane
15	C3H6O	acetone

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	2 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	3 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	4 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	5 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	6 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	7 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	8 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	9 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	10 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	11 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	12 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	13 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	14 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4
POMD	15 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	4

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubilities of Betulin in Fourteen Organic Solvents at Different Temperatures

Cao, D.[Dan], Zhao, G.[Guoling], Yan, W.[Weidong]

ABSTRACT