ABSTRACT

The solubilities of rutaecarpine in 12 organic solvents (dichloromethane, ethyl acetate, acetone, trichloromethane, ethoxyethane, butyl alcohol, isopropyl alcohol, ethyl alcohol, methyl alcohol, cyclohexane, hexane, and pentane) were measured over the temperature range of (283.2 to 323.2) K. The solubilities of rutaecarpine in selected organic solvents increase with the increasing of the temperature and were correlated by the modified Apelblat equation and a simplified thermodynamic equation. The dissolution enthalpy and entropy of rutaecarpine in these solvents were calculated using the van t Hoff equation. The results showed that the dissolution process was endothermic and entropy-driven.

Compounds

#	Formula	Name
1	C18H13N3O	Rutecarpine
2	CH2Cl2	dichloromethane
3	C4H8O2	ethyl acetate
4	C3H6O	acetone
5	CHCl3	trichloromethane
6	C4H10O	diethyl ether
7	C4H10O	butan-1-ol
8	C3H8O	propan-2-ol
9	C2H6O	ethanol
10	CH4O	methanol
11	C6H12	cyclohexane
12	C6H14	hexane
13	C5H12	pentane

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	2 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	1 3	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	4 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	5 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	6 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	7 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	8 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	9 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	10 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	1 11	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	1 12	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5
POMD	1 13	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	5

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubilities of Rutaecarpine in Twelve Organic Solvents from (283.2 to 323.2) K

Fan, J.-P.[Jie-Ping], Xie, Y.-L.[Yan-Long], Tian, Z.-Y.[Ze-You], Xu, R.[Rui], Qin, Y.[Yu], Li, L.[Lie], Zhu, J.-H.[Jian-Hang], Zhang, X.-H.[Xue-Hong]

ABSTRACT