Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Vaporization Enthalpy and Vapor Pressure of Valproic Acid by Correlation Gas Chromatography

Wilson, J. A., Chickos, J.[James]
J. Chem. Eng. Data 2012, 57, 8, 2281-2285
ABSTRACT
The vaporization enthalpy of valproic acid (2-propylpentanoic acid) is reported, and the vapor pressures of a series on aliphatic carboxylic acids are used to evaluate its vapor pressure as a function of temperature. The vaporization enthalpy was derived by correlation-gas chromatography. This resulted in a vaporization enthalpy, ?Hvap(298.15 K) of (74.8 +- 2.4) kJ*mol 1. Vapor pressures from T/K = 298.15 to boiling temperature of valproic acid are also reported. A normal boiling temperature of T/K = 492.8 (lit., 494 5 K) and a vapor pressure of (2.2 +- 0.3) Pa has been evaluated for valproic acid at T/K = 298.15. This compares favorably with an Environmental Protection Agency estimate of 6.1 Pa.
Compounds
# Formula Name
1 C8H16O2 2-propylpentanoic acid
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • Molar enthalpy of transition or fusion, kJ/mol ; Liquid
  • Temperature, K; Liquid
  • Liquid
  • Gas
  • Correlation gas chromatography
  • 1
  • POMD
  • 1
  • Vapor or sublimation pressure, kPa ; Liquid
  • Temperature, K; Liquid
  • Liquid
  • Gas
  • Gas chromatography
  • 40