Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Measurement and Correlation of the Solubility of 2,6-Diaminohexanoic Acid Hydrochloride in Aqueous Methanol and Aqueous Ethanol Mixtures

Sun, H.[Hua], Li, M.[Min], Jia, J.[Jingtan], Tang, F.[Fengkui], Duan, E.[Erhong]
J. Chem. Eng. Data 2012, 57, 5, 1463-1467
ABSTRACT
The solubility of 2,6-diaminohexanoic acid hydrochloride in three pure and aqueous alcohols (methanol and ethanol) was measured by a dynamic method with a laser monitoring technique in the temperature range from 283.15 K to 333.15 K. The solubility in the different solvents increases in the following order: water greater than methanol greater than ethanol. In binary solvents, the solubility decreases with increasing alcohol concentration. The solubility data were correlated with the combined nearly ideal binary solvent/Redlich Kister (CNIBS/R-K) model and a modified Jouyban Acree model. For the five solvents studied, the CNIBS/R-K model was found to provide a more accurate mathematical representation of the experimental data, while the modified Jouyban Acree model contained provisions for correlating both solvent composition and temperature.
Compounds
# Formula Name
1 C6H15ClN2O2 L-lysine monohydrochloride
2 H2O water
3 CH4O methanol
4 C2H6O ethanol
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • laser monitoring
  • 6
  • POMD
  • 3
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • laser monitoring
  • 6
  • POMD
  • 4
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • laser monitoring
  • 6
  • POMD
  • 3
  • 1
  • 2
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 3; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • laser monitoring
  • 36
  • POMD
  • 4
  • 1
  • 2
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 4; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • laser monitoring
  • 36