Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Determination and Correlation for Solubilities of Ofloxacin, Norfloxacin, Lomefloxacin, Ciprofloxacin, Pefloxacin, and Pipemidic Acid in 1-Octanol from (293.15 to 333.15) K

Zhang, C.-L.[Cong-Liang], Wang, Y.[Yan]
J. Chem. Eng. Data 2010, 55, 9, 4033-4035
ABSTRACT
The solubilities of ofloxacin, norfloxacin, lomefloxacin, ciprofloxacin, pefloxacin, and pipemidic acid in 1-octanol have been determined from (293.15 to 333.15) K by a static equilibrium method. The experimental data were correlated with the modified Apelblat equation.
Compounds
# Formula Name
1 C18H20FN3O4 ofloxacin
2 C16H18FN3O3 norfloxacin
3 C17H19F2N3O3 lomefloxacin
4 C17H18FN3O3 ciprofloxacin
5 C17H20FN3O3 pefloxacin
6 C14H17N5O3 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acid
7 C8H18O octan-1-ol
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 7
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Static equilibrium method
  • 9
  • POMD
  • 7
  • 2
  • Mole fraction - 2 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 2
  • Static equilibrium method
  • 9
  • POMD
  • 7
  • 3
  • Mole fraction - 3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 3
  • Static equilibrium method
  • 9
  • POMD
  • 7
  • 4
  • Mole fraction - 4 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 4
  • Static equilibrium method
  • 9
  • POMD
  • 7
  • 5
  • Mole fraction - 5 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 5
  • Static equilibrium method
  • 9
  • POMD
  • 7
  • 6
  • Mole fraction - 6 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 6
  • Static equilibrium method
  • 9