Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Ceftriaxone Disodium in Acetone, Methanol, Ethanol, N,N-Dimethylformamide, and Formamide between 278 and 318 K

Zhang, C.[Chuntao], Wang, J.[Jingkang], Wang, Y.[Yongli]
J. Chem. Eng. Data 2005, 50, 5, 1757-1760
ABSTRACT
Experimental results are reported for the solubility of ceftriaxone disodium in acetone, methanol, ethanol, formamide, and N,N-dimethylformamide between 278 and 318 K. The isothermal method and the laser monitoring observation technique were used for the determination of the mole fraction concentration. The solubility of ceftriaxone disodium in pure solvents increases with increasing temperature and in the following order: acetone < ethanol < N,N-dimethylformamide < methanol < formamide. The experimental solubility data were correlated with a semiempirical equation.
Compounds
# Formula Name
1 C18H16N8Na2O7S3 disodium ceftriaxone
2 C3H6O acetone
3 CH4O methanol
4 C2H6O ethanol
5 C3H7NO dimethylformamide
6 CH3NO formamide
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser intensity
  • 10
  • POMD
  • 3
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser intensity
  • 10
  • POMD
  • 4
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser intensity
  • 10
  • POMD
  • 5
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser intensity
  • 10
  • POMD
  • 6
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Laser intensity
  • 9