The equilibrium solubilities of gatifloxacin in four non-aqueous solvent mixtures of N,N-dimethylformamide (DMF,1) + methanol (2), DMF (1) + ethanol (2), DMF (1) + isopropanol (2) and DMF (1) + n-propanol (2) were studied at the temperatures from 273.15 to 318.15 K K under local pressure of 101.1 kPa. The solubility values of gatifloxacin increased with a rise of mass fraction of DMF and temperature for each system. At the same DMF composition and temperature, the mole fraction solubilities of gatifloxacin were largest in the DMF (1) + n-propanol (2) mixture. The attained solubility was represented mathematically by the Jouyban-Acree, van't Hoff-Jouyban-Acree and Apelblat-Jouyban-Acree models acquiring average relative deviations smaller than 2.49 % and root-mean-square deviation smaller than 1.15 10-4.
Compounds
#
Formula
Name
1
C19H22FN3O4
gatifloxacin
2
C3H8O
propan-2-ol
3
C3H7NO
dimethylformamide
4
CH4O
methanol
5
C2H6O
ethanol
6
C3H8O
propan-1-ol
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.