ABSTRACT

The mole fraction solubility data of -proline in five monosolvents (water, methanol, ethanol, acetone, and acetonitrile) and four binary solvent systems (methanol + acetone, ethanol + acetone, methanol + acetonitrile, and ethanol + acetonitrile) were experimentally measured by gravimetric method at temperatures ranging from 283.15 to 323.15 K. The results showed that L-proline solubility and experimental temperature were positively correlated when the solvent composition was constant. On the basis of the solubility scatter diagrams and our investigation of solvent properties, the solubility behavior of L-proline in the pure and binary solvent systems was influenced by a combination of many factors. The solubility data were correlated by three thermodynamic models including the modified Apelblat, CNIBS/R-K, and Apelblat-Jouyban-Acree models. The fitting results were generally acceptable.

Compounds

#	Formula	Name
1	C5H9NO2	L-proline
2	CH4O	methanol
3	C2H6O	ethanol
4	C3H6O	acetone
5	C2H3N	acetonitrile
6	C5H12O5	xylitol
7	C12H24O11	4-O-.alpha.-D-glucopyranosyl-D-glucitol
8	H2O	water

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1 8	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	5
POMD	1 2	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	5
POMD	1 3	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	5
POMD	1 4	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	5
POMD	1 5	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	5
POMD	1 2 4	Mole fraction - 1 ; Liquid	Temperature, K; Liquid Solvent: Mole fraction - 2; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	55
POMD	1 3 4	Mole fraction - 1 ; Liquid	Temperature, K; Liquid Solvent: Mole fraction - 3; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	55
POMD	1 2 5	Mole fraction - 1 ; Liquid	Temperature, K; Liquid Solvent: Mole fraction - 2; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	55
POMD	1 3 5	Mole fraction - 1 ; Liquid	Temperature, K; Liquid Solvent: Mole fraction - 3; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	55
POMD	6 3	Mole fraction - 6 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 6	gravimetric	6
POMD	7 8 3	Mole fraction - 7 ; Liquid	Temperature, K; Liquid	Solvent: Mole fraction - 8; Liquid Pressure, kPa; Liquid	Liquid Crystal - 7	gravimetric	6
POMD	1 8 3	Mole fraction - 1 ; Liquid	Solvent: Mole fraction - 8; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	3

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility Behavior and Data Modeling of l-Proline in Different Neat and Binary Solvent Systems

Qiu, J.[Jingxuan], Huang, H.[Haishuang], He, H.[Hui], Liu, H.[Haoyou], Hu, S.[Shen], Han, J.[Jiaming], Yi, D.[Dengjing], An, M.[Mengyao], Wang, P.[Peng]

ABSTRACT