ABSTRACT

The solubility of -Arbutin (ARB) in 12 different mono-solvents (methanol, ethanol, propanol, isopropanol, butyl alcohol, isobutanol, ethyleneglycol, acetone, 2-butanone, acetonitrile, methyl acetate, ethyl acetate) from 283.15 K to 323.15 K at atmospheric pressure was measured by gravimetric method. The solubility data shows an increasing trend with increasing temperature. The solubility is related to many factors like polarity, H-bond and cohesive energy density etc. The solubility of ARB was correlated by the Apelblat model, h equation, Van't Hoff equation and NRTL model. And the Apelblat model shows a better fitting result compared that with other three models through calculating the value of ARD. Besides, the dissolution thermodynamic properties (the dissolution Gibbs energy, enthalpy and entropy) were evaluated, which reveals that the dissolution of ARB is a spontaneous and exothermic process.

Compounds

#	Formula	Name
1	C12H16O7	.beta.-arbutin
2	CH4O	methanol
3	C2H6O	ethanol
4	C3H8O	propan-1-ol
5	C3H8O	propan-2-ol
6	C4H10O	butan-1-ol
7	C4H10O	2-methyl-1-propanol
8	C2H6O2	1,2-ethanediol
9	C3H6O	acetone
10	C4H8O	butanone
11	C2H3N	acetonitrile
12	C3H6O2	methyl ethanoate
13	C4H8O2	ethyl acetate

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1	Triple point temperature, K ; Crystal			Crystal Liquid Air at 1 atmosphere	DSC	1
POMD	1	Molar enthalpy of transition or fusion, kJ/mol ; Crystal			Crystal Liquid Air at 1 atmosphere	DSC	1
POMD	1 2	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 3	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 4	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 5	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 6	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 7	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 8	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 9	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 10	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 11	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 12	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9
POMD	1 13	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	gravimetric	9

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility and Data Correlation of b-Arbutin in Different Monosolvents from 283.15 to 323.15 K

Liu, F.[Fei], Qu, H.[Haibin], Wan, X.[Xuxing], Han, D.[DanDan], Li, W.[Wenlong], Wu, S.[Songgu]

ABSTRACT