Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

ABSTRACT

In this research, the purpose is to study the solid-liquid equilibrium solubility of pymetrozine and the influence of the solvent effect on solubility. The solubility of pymetrozine was measured by using a static equilibrium method. The solubility of pymetrozine increases with increasing temperature, and the solubility from high to low is dimethyl sulfoxide (DMSO, 0.8623 * 10-2 , 298.15 K) greater than N,Ndimethylformamide (DMF, 0.5147 * 10-2 , 298.15 K) greater than N-methyl pyrrolidone (NMP, 0.2946 * 10-2 , 298.15 K) greater than 1,4-dioxane (0.6289 * 10-3 , 298.15 K) greater than 2- propanol (0.3913 * 10-3 , 298.15 K) greater than 1-butanol (0.3319 * 10-3 , 298.15 K); moreover, in the binary solvents system, solubility increases to a maximum with increasing temperature and DMF (and NMP, DMSO, 1,4-dioxane) and then decreases with further increase of the cosolvent. The relationships between solubility and temperature together with solvent composition were described by six common models. The values of relative average deviation and root-mean-square deviation were no larger than 1.03% and 6.70 * 10-5 , respectively. In order to choose the best model for pymetrozine, the Akaike information criterion (AIC) was used for assessing the relative suitability of selected models. Compared with calculation results of above models, the Apelblat equation is the best model for solubility correlation of pymetrozine in monosolvents because the value of AIC of the Apelblat equation is lowest and the value is -1113.03; besides, for mixed solvents, the Jouyban-Acree model is the best model. All in all, these correlation models were all appositeness for the solubility of pymetrozine in all experimental solvent systems.