Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

ABSTRACT

Solubility and thermodynamic data of 3-Methyl-6-nitroindazole in eight pure solvents and three mixed solvents were obtained experimentally via the static equilibrium method within the temperature range of (278.15-328.15) K under atmospheric pressure. Whether in pure solvent system or a mixed system, the results show that mole fraction solubilities of 3-Methyl-6nitroindazole increased with increasing temperature. The maximum mole fraction solubilities of 3Methyl-6-nitroindazole was recorded in neat DMF and the minimum in water. The molecular interactions of 3-Methyl-6-nitroindazole with solvents were determined by the determination of activity coefficients of 3-Methyl-6-nitroindazole. Among the three groups of mixed solvents measuredthe molar fraction of 3-Methyl-6-nitroindazole in (DMF+water) system is the maximum. The experimental solubility values of 3-Methyl-6-nitroindazole were fitted well with five versatile models with R2 value of greater than0.99.