Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

ABSTRACT

Solubility of 4-aminobenzamide was measured by a gravimetric method in ethyl acetate, butyl acetate, methyl acetate, methanol, ethanol, isobutanol, 1-butanol, acetonitrile, isopropanol, acetone, water, and 1-propanol at varied temperatures between 283.15 K and 323.15 K. Modified Apelblat model, NRTL model, and Wilson model were applied to correlate the relationship between the temperature and solubility, and the model parameters and data error were calculated and compared with each other. Results revealed that the best correlation accuracy was obtained by modified Apelblat model. Furthermore, dissolution Gibbs energy disG, dissolution entropy disS, and dissolution enthalpy disH were determined based on the solubility data, and the three dissolution thermodynamic properties were also discussed to investigate the dissolution behavior of 4-aminobenzamide.