Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

ABSTRACT

The experimental solubility data of L-Glutamic acid in pure water, formic acid, methanol, 1-proanol, 2-propanol, acetonitrile and binary mixtures (formic acid + water, methanol + water, 2-propanol + water, acetonitrile + water) with different compositions were carried out at temperatures ranging from (283.15 to 328.15) K by the static analytic method. The solubility measurements showed that formic acid and its aqueous mixtures recorded higher solubility than methanol + water, 2-propanol + water, acetonitrile + water for the same composition at each temperature. Moreover, except formic acid the addition of methanol, 2-propanol & acetonitrile to its aqueous mixtures resulted in the decrease in solubility of L-glutamic acid. The experimental data was fitted using different thermodynamic models such as Buchowski-Ksiazczak equation, the Van't Hoff equation, the modified Apelblat equation and NRTL model and the optimum values of the regressed parameters were obtained. The modified Apelblat equation, BuchowskiKsiazczak equation and NRTL activity coefficient model were fitted to the pure solvents solubility data, while modified Apelblat, modified Apelblat-Jouyban-Acree and the NRTL model were used for the binary solvent systems. The results demonstrated that formic acid as a cosolvent in the dissolution of L-glutamic acid in formic acid + water binary mixtures, while others exhibited an antisolvent effect on the solubilization of L-glutamic acid in their respective aqueous mixtures.