Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

ABSTRACT

The equilibrium solubility of 4-amino-2,6-dimethoxypyrimidine in solvent mixtures of methanol (1) + water (2), ethanol (1) + water (2), isopropanol (1) + water (2) and N,N-dimethylformamide (1, DMF) + water (2) were determined experimentally by using isothermal dissolution equilibrium method within the temperature ranging from (283.15 to 323.15) K under atmospheric pressure (101.1 kPa). The solubility of 4-amino-2,6-dimethoxypyrimidine increased monotonously with the increase in mass fraction of methanol, ethanol, isopropanol and DMF and temperature. At the same temperature and mass fraction of methanol (ethanol, isopropanol and DMF), the mole fraction solubility of 4-amino-2,6-dimethoxypyrimidine is greater in (DMF + water) than in the other three solvent mixtures. Besides, the solubilities of 4-amino-2,6-dimethoxypyrimidine were correlated with