ABSTRACT

This work is to research the influence of different solvent properties and the composition on the solubility of iopromide. The solubility values of iopromide in some pure and binary solvent mixtures have been measured from T=273.15 to 318.15 K. The result showed that the solubility obtained a maximum value in mole fraction (x= 55.426x10-4 at T =318.15K) in pure N, N-dimethylformamide (DMF) and the minimum data (x= 9.9x10-6 at T =273.15K) in neat toluene. The values in pure solvents obeyed the following order: DMF greater than methanol greater than ethanol greater than isopropanol greater than acetone greater than ethyl acetate greater than toluene. In mixed solvents, it was increased with increasing mass fraction of DMF at given temperature. Moreover, the obtained solubility data in

Compounds

#	Formula	Name
1	C18H24I3N3O8	iopromide
2	CH4O	methanol
3	C2H6O	ethanol
4	C3H8O	propan-2-ol
5	C3H6O	acetone
6	C4H8O2	ethyl acetate
7	C7H8	toluene
8	C3H7NO	dimethylformamide
9	C7H6O2	benzoic acid

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1 2	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	1 3	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	1 4	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	1 5	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	1 6	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	1 7	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	1 8	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	1 8 3	Mole fraction - 1 ; Liquid	Solvent: Mass fraction - 8; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	110
POMD	9 7	Mole fraction - 9 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 9	Chromatography	3

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Influence of Different Solvent Properties and Composition for the Solubility of Iopromide

Xu, Renjie, Han, Ting

ABSTRACT