Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility of Azoxystrobin and Benflumetol in Compressed CO2-Measured by the Static Precise Mass Measuring Method

Li, Qingguo, Pan, Piaopiao, Lu, Tiejun, Blackburn, Stuart, Leeke, Gary A.
J. Chem. Eng. Data 2019, 64, 1, 9-15
ABSTRACT
The solubility of hardly soluble solutes in compressed CO2 was measured using a new Static Precise Mass Measuring (SPMM) method. The solubility of two solutes, azoxystrobin a substituted pyrimidine, and benflumetol an anti-malarial drug were determined at pressures and temperatures from 80 to 250 bar and 301K to 323K. Solubility of these two compounds were 64-661 mg/kg CO2 and 1.3-19.7 mg/kg CO2, respectively. The measured solubility was correlated using the density-based model proposed by Chrastil and theory of dilute solutions based model proposed by MendezSantiago and Teja. A linear relationship between the solubility and the solvent density was obtained.
Compounds
# Formula Name
1 C22H17N3O5 azoxystrobin
2 C30H32Cl3NO benflumetol
3 CO2 carbon dioxide
4 C8H10N4O2 caffeine
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 3
  • Mass ratio of solute to solvent - 1 ; Fluid (supercritical or subcritical phases)
  • Temperature, K; Fluid (supercritical or subcritical phases)
  • Pressure, kPa; Fluid (supercritical or subcritical phases)
  • Fluid (supercritical or subcritical phases)
  • Crystal - 1
  • gravimetric
  • 12
  • POMD
  • 2
  • 3
  • Mass ratio of solute to solvent - 2 ; Fluid (supercritical or subcritical phases)
  • Temperature, K; Fluid (supercritical or subcritical phases)
  • Pressure, kPa; Fluid (supercritical or subcritical phases)
  • Fluid (supercritical or subcritical phases)
  • Crystal - 2
  • gravimetric
  • 18
  • POMD
  • 4
  • 3
  • Mass ratio of solute to solvent - 4 ; Fluid (supercritical or subcritical phases)
  • Pressure, kPa; Fluid (supercritical or subcritical phases)
  • Temperature, K; Fluid (supercritical or subcritical phases)
  • Fluid (supercritical or subcritical phases)
  • Crystal - 4
  • gravimetric
  • 3