Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

ABSTRACT

The knowledge of solubility and solution thermodynamics for 3-nitroacetophenone and 4-nitroacetophenone in different solvents is essential for its purification and further theoretical studies. In this work, the solid-liquid equilibrium for 3-nitroacetophenone and 4-nitroacetophenone in nine pure solvents (methanol, ethanol, n-propanol, isopropanol, acetone, acetonitrile, ethyl acetate, toluene and cyclohexane) was established with the isothermal saturation method at temperatures T = (278.15 to 318.15) K under pressure of 101.2 kPa. The mole fraction solubility obeyed the following order from high to low in different solvents: acetone greater than acetonitrile greater than ethyl acetate greater than toluene greater than methanol greater than ethanol greater than n-propanol greater than isopropanol greater than cyclohexane, but the solubility of 3-nitroacetophenone in isopropanol is larger than in n-propanol at temperature below 293.15K, and vice versa at above 298.15K. The modified Apelblat equation, h equation, Wilson model and NRTL model were employed to correlate the measured solubility data of 3-nitroacetophenone and 4-nitroacetophenone in the selected solvents. Results showed that the