Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

ABSTRACT

The solubility of dipyridamole p-toluene sulfonate in seven mono-solvents (methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, isobutanol, 2-butanol) and three different binary solvents (methanol + ethanol, methanol + 1-propanol, methanol + 1-butanol) was measured by a gravimetric method at temperatures ranging from 288.15 K to 328.15 K. The experimental results indicate that the solubility of dipyridamole p-toluene sulfonate increases with increasing temperature while shows negative correlation with the mole fraction of organic solvents (ethanol, 1-propanol, 1-butanol) at a given temperature in binary solvents. The Apelblat model, the CNIBS/R-K model and the modified version of Jouyban-Acree models (the Apel-JA equation) were used to correlate the experimental data, and the calculated results of above models were found to agree well with the experimental data.