Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

ABSTRACT

Mono-nitro substituted products derived from the nitration of m-Toluic acid are 3-methyl-4-nitrobenzoic acid, 3-methyl-2-nitrobenzoic acid and 5-methyl-2-nitrobenzoic acid, which are all crucial intermediates of pesticides and medicines. The solubilities of 3-methyl-4-nitrobenzoic acid, 3-methyl-2-nitrobenzoic acid and 5-methyl-2-nitrobenzoic acid in water, methanol, ethanol, n-propanol, formic acid, acetic acid and propanoic acid were measured at different temperatures (297.65 to 351.75 K) and under atmospheric pressure, respectively. As expected, the same solute has different solubilities in different solvents, and the dissolved amounts of these three solutes are also diverse in the same solvent. Subsequently the experimental solubility data of three mono-nitro substituted products of m-Toluic acid nitration in several solvents were correlated with the modified Apelblat equation and the NRTL activity coefficient model, and the calculated values are in good agreement with experimental data in the temperature range studied.