ABSTRACT

The solubilities of phloretin, phlorizin, and naringin dihydrochacone (naringin DC) respectively were determined in a ternary system made of natural deep eutectic solvents (NADES) at the temperature range from 288.15 to 328.15 K with an analytical method. Compared with the solubility of phloretin in water, there was a dramatic improvement in the solubility of phloretin in the selected NADES, especially in CCiH and CSH. The density and viscosity of four kinds of NADES choline chloride + glucose + H2O, choline chloride + citric acid + H2O, citric acid + glucose + H2O, and choline chloride + sucrose + H2O were studied in this work. The solubility data were correlated with Apelblat equation and h equation. The fitted results showed that the models are capable of representing the data with high accuracy.

Compounds

#	Formula	Name
1	C15H14O5	3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
2	C21H24O10	phlorizin
3	C27H34O14	naringin dihydrochalcone
4	C5H14ClNO	choline chloride
5	C6H8O7	citric acid
6	C6H12O6	D-glucose
7	C12H22O11	D-sucrose
8	H2O	water
9	C14H10O2	1,2-diphenylethanedione
10	C3H6O2	methyl ethanoate
11	C2H3N	acetonitrile

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1	Triple point temperature, K ; Crystal			Crystal Liquid Air at 1 atmosphere	DSC	1
POMD	1	Molar enthalpy of transition or fusion, kJ/mol ; Crystal			Crystal Liquid Air at 1 atmosphere	DSC	1
POMD	2	Triple point temperature, K ; Crystal			Crystal Liquid Air at 1 atmosphere	DSC	1
POMD	2	Molar enthalpy of transition or fusion, kJ/mol ; Crystal			Crystal Liquid Air at 1 atmosphere	DSC	1
POMD	3	Triple point temperature, K ; Crystal			Crystal Liquid Air at 1 atmosphere	DSC	1
POMD	3	Molar enthalpy of transition or fusion, kJ/mol ; Crystal			Crystal Liquid Air at 1 atmosphere	DSC	1
POMD	6 5 8	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Amount ratio of solute to solvent - 5; Liquid Amount ratio of solute to solvent - 6; Liquid Pressure, kPa; Liquid	Liquid	Vibrating tube method	7
POMD	6 5 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Amount ratio of solute to solvent - 5; Liquid Amount ratio of solute to solvent - 6; Liquid Pressure, kPa; Liquid	Liquid	Concentric cylinders viscometry	7
POMD	4 5 8	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Amount ratio of solute to solvent - 4; Liquid Amount ratio of solute to solvent - 5; Liquid Pressure, kPa; Liquid	Liquid	Vibrating tube method	7
POMD	4 5 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Amount ratio of solute to solvent - 4; Liquid Amount ratio of solute to solvent - 5; Liquid Pressure, kPa; Liquid	Liquid	Concentric cylinders viscometry	7
POMD	6 4 8	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Amount ratio of solute to solvent - 4; Liquid Amount ratio of solute to solvent - 6; Liquid Pressure, kPa; Liquid	Liquid	Vibrating tube method	7
POMD	6 4 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Amount ratio of solute to solvent - 4; Liquid Amount ratio of solute to solvent - 6; Liquid Pressure, kPa; Liquid	Liquid	Concentric cylinders viscometry	7
POMD	7 4 8	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Amount ratio of solute to solvent - 4; Liquid Amount ratio of solute to solvent - 7; Liquid Pressure, kPa; Liquid	Liquid	Vibrating tube method	7
POMD	7 4 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Amount ratio of solute to solvent - 4; Liquid Amount ratio of solute to solvent - 7; Liquid Pressure, kPa; Liquid	Liquid	Concentric cylinders viscometry	7
POMD	10 9	Mole fraction - 9 ; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid		Liquid Crystal - 9	Chromatography	1
POMD	11 9	Mole fraction - 9 ; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid		Liquid Crystal - 9	Chromatography	1

Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubilities of Three Flavonoids in Different Natural Deep Eutectic Solvents at T = (288.15 to 328.15) K

Tang, N.[Ning], Zhong, J.[Jialun], Yan, W.[Weidong]

ABSTRACT