Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubilities of Naringin Dihydrochalcone in Pure Solvents and Mixed Solvents at Different Temperatures

Tang, N.[Ning], Yan, W.[Weidong]
J. Chem. Eng. Data 2016, 61, 12, 4085-4089
ABSTRACT
Naringin dihydrochalcone (naringin DC) is an intense sweetener and a strong antioxidant with potential applications in many food and pharmaceutical products. However, the poor solubility and stability of naringin DC in aqueous systems at room temperature severely limits its applications in these areas. The solubility of naringin dihydochalone was quantified in water, ethyl acetate, binary solvent mixtures of methanol + water and ethanol + water by a synthetic method at different temperatures. The solubility of naringin DC in a given solvent increases with the rising temperature. The experimental data were well correlated with an Apelblat equation and Universal Quasichemical model. Moreover, the physical properties and crystal habit of naringin DC were discussed through a thermogravimetric analyzer, a differential scanning colorimeter, and a scanning electron microscope.
Compounds
# Formula Name
1 C27H34O14 naringin dihydrochalcone
2 CH4O methanol
3 C2H6O ethanol
4 C4H8O2 ethyl acetate
5 H2O water
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • Normal melting temperature, K ; Crystal
  • Crystal
  • Liquid
  • Air at 1 atmosphere
  • DTA
  • 1
  • POMD
  • 1
  • Molar enthalpy of transition or fusion, kJ/mol ; Crystal
  • Crystal
  • Liquid
  • Air at 1 atmosphere
  • DSC
  • 1
  • POMD
  • 5
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Titration method
  • 5
  • POMD
  • 4
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Titration method
  • 5
  • POMD
  • 2
  • 5
  • 1
  • Mole fraction - 1 ; Liquid
  • Solvent: Mole fraction - 2; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Titration method
  • 10
  • POMD
  • 3
  • 5
  • 1
  • Mole fraction - 1 ; Liquid
  • Solvent: Mole fraction - 3; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Titration method
  • 10