Thermodynamics Research Center / ThermoML | Journal of Chemical and Engineering Data

Solubility, Density, and Metastable Zone Width of Pyridoxine Hydrochloride in Water and Ethanol Solvent Mixtures

Zhou, K.[Kun], Yan, Y.[Yueyong], An, L.[Lianying], Xiang, D.[Dongni], Wang, H.[Hongbin]
J. Chem. Eng. Data 2016, 61, 1, 307-312
ABSTRACT
The solubility of pyridoxine hydrochloride in water and ethanol solvent mixtures was measured using a laser monitoring observation technique at the temperature range from (278.15 to 323.15) K. The mole fraction of ethanol in the solvent mixtures (x3) ranges from 0.0 to 0.6012. For the seven group data studied, the experimental solubility data were well-correlated with the results calculated by means of a semiempirical equation. Densities of pyridoxine hydrochloride in solvent mixtures were investigated at temperatures from (293.15 to 323.15) K. The effects of ethanol mole fraction, cooling rate, and saturation temperature on the metastable zone width (MZW) were also studied. The results show that the MZW of pyridoxine hydrochloride becomes narrower by increasing the saturation temperature, increasing ethanol mole fraction, and reducing the cooling rate. For the density and the MZW, all results were correlated by empirical equations.
Compounds
# Formula Name
1 C8H12ClNO3 5-hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride
2 H2O water
3 C2H6O ethanol
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 3
  • 2
  • Mole fraction - 1 ; Liquid
  • Solvent: Mole fraction - 3; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • UV Spectrometry
  • 70
  • POMD
  • 1
  • 3
  • 2
  • Mass density, kg/m3 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 3; Liquid
  • Mole fraction - 1; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Vibrating tube method
  • 28
  • POMD
  • 1
  • 2
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • UV Spectrometry
  • 10
  • POMD
  • 1
  • 2
  • Mass density, kg/m3 ; Liquid
  • Temperature, K; Liquid
  • Mole fraction - 1; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Vibrating tube method
  • 7