The solubility of the biologically active substances - salinazid and vanillin isoniazid was measured in the buffer solutions (oI 2.0 and 7.4), and octanol within the temperature range from (293.15 to 313.15) K. The solubility of the compounds in all the investigated solvents was revealed to be less than 10-3 mole fraction and increases with the solvents in the order: buffer pH 7.4 less than buffer pH 2.0 less than octanol. The thermodynamic functions of dissolution and solvation were calculated. The temperature dependences of the distribution coefficients in the system buffer pH 7.4/octanol system were obtained and the transfer thermodynamic functions were derived. The distribution coefficients were used to predict the solubility of the studied compounds in aqueous medium.
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.