Novel experimental data for physicochemical properties of the bioactive compound N-(5-ethyl-1,3,4-thiadiazole- 2-yl)-4-nitrobenzamide have been obtained. The saturated vapor pressure of the studied compound has been measured within the temperature range of 431.15 457.15 K by the inert gas transpiration method. The shake flask method has been used to determine the solubility in buffer pH 7.4, n-hexane, ethanol, 1-octanol and distribution coefficients in the 1-octanol/buffer system at different temperatures. The van't Hoff and modified Apelblat models have been used to correlate the experimental solubility. The thermodynamic functions of sublimation and transfer have been investigated and discussed.
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.
Type
Compound-#
Property
Variable
Constraint
Phase
Method
#Points
POMD
1
Normal melting temperature, K ; Crystal
Crystal
Liquid
Air at 1 atmosphere
DTA
1
POMD
1
Molar enthalpy of transition or fusion, kJ/mol ; Crystal