ABSTRACT

Thermodynamic properties of aqueous solutions of some amino acids, glycine and l-alanine with a novel ionic liquid containing salicylate anion, 1-butyl-3-methylimidazolium salicylate, [BMIM][SAL] as an active pharmaceutical ingredient ionic liquid (API-IL) have been investigated by volumetric, ultrasonic, refractometric and viscometric properties at T = (288.15.318.15 K). The standard partial molar volume, partial molar volume of transfer, Hepler's constant and apparent molar isentropic compressibility have been calculated from density and speed of sound data. Viscosity and refractive index data were used for determination of viscosity B-coefficients, hydration number and molar refraction parameters. These parameters are helpful to study the structure promoting and solvation behaviour of the API-IL and various interactions present in the ternary solutions of (amino acid + [BMIM][SAL] + water).

Compounds

#	Formula	Name
1	C2H5NO2	2-aminoacetic acid
2	C3H7NO2	(S)-2-aminopropanoic acid
3	C15H20N2O3	1-butyl-3-methylimidazolium salicylate
4	H2O	water

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	4
POMD	3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	4
POMD	3	Refractive index (Na D-line) ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Standard Abbe refractometry	4
POMD	2 4 3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid Solvent: Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	144
POMD	2 4 3	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid Solvent: Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Falling or rolling sphere viscometry	144
POMD	2 4 3	Refractive index (Na D-line) ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid Solvent: Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Standard Abbe refractometry	144
POMD	2 4 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid Solvent: Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	144
POMD	1 4 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid Solvent: Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	144
POMD	1 4 3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid Solvent: Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	144
POMD	1 4 3	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid Solvent: Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Falling or rolling sphere viscometry	144
POMD	1 4 3	Refractive index (Na D-line) ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid Solvent: Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Standard Abbe refractometry	124
POMD	4 3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	28
POMD	4 3	Refractive index (Na D-line) ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Standard Abbe refractometry	28
POMD	4 3	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Falling or rolling sphere viscometry	24
POMD	4 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	28

Thermodynamics Research Center / ThermoML | Thermochimica Acta

Thermodynamic properties of 1-butyl-3-methylimidazolium salicylate as an active pharmaceutical ingredient ionic liquid (API-IL) in aqueous solutions of glycine and L-alanine at T = (288.15 318.15) K

Shekaari, H.[Hemayat], Zafarani-Moattar, M. T.[Mohammed Taghi], Mirheydari, S. N.[Seyyedeh Narjes]

ABSTRACT