ABSTRACT

This paper reports density, speed of sound, and viscosity data for the bile salts: sodium cholate (1-30mmolkg-1) and sodium deoxycholate (1-17mmolkg-1) in 0.1 mol kg 1 aqueous solution of amino acids viz. glycine, leucine, methionine, and histidine at different temperatures (293.15-318.15 K) under atmospheric pressure. From the experimental density and speed of sound data, the apparent molar volume (fv), isentropic compressibility (ks), and apparent molar isentropic compression (fk) have been calculated, and the results have been interpreted in terms of different hydrophobic and electrostatic interactions pertaining in the bile salt amino acid water ternary system. Based on experimental viscosity data, the relative viscosity (hr) and viscous relaxation time (t) have been calculated and their dependence on concentration of bile salts and temperature has confirmed the existence of significant amount of bile salt amino acid interactions

Compounds

#	Formula	Name
1	H2O	water
2	C24H39NaO5	sodium cholate
3	C24H39NaO4	sodium deoxycholate
4	C2H5NO2	2-aminoacetic acid
5	C6H13NO2	L-leucine
6	C5H11NO2S	L-methionine
7	C6H9N3O2	L-histidine

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	6
POMD	1	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	6
POMD	1	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	6
POMD	2 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	78
POMD	2 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	2 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	7 2 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 7; Liquid	Liquid	Vibrating tube method	78
POMD	7 2 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 7; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	7 2 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 7; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	4 2 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 4; Liquid	Liquid	Vibrating tube method	78
POMD	4 2 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 4; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	4 2 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 4; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	6 2 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 6; Liquid	Liquid	Vibrating tube method	78
POMD	6 2 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 6; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	6 2 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 6; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	5 2 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 5; Liquid	Liquid	Vibrating tube method	78
POMD	5 2 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 5; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	5 2 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 2; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 5; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	3 1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	78
POMD	3 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	3 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	7 3 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 7; Liquid	Liquid	Vibrating tube method	78
POMD	7 3 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 7; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	7 3 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 7; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	4 3 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 4; Liquid	Liquid	Vibrating tube method	78
POMD	4 3 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 4; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	4 3 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 4; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	6 3 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 6; Liquid	Liquid	Vibrating tube method	78
POMD	6 3 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 6; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	6 3 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 6; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	5 3 1	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 5; Liquid	Liquid	Vibrating tube method	78
POMD	5 3 1	Speed of sound, m/s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 5; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	78
POMD	5 3 1	Viscosity, Pa*s ; Liquid	Molality, mol/kg - 3; Liquid Temperature, K; Liquid	Pressure, kPa; Liquid Solvent: Molality, mol/kg - 5; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	78
POMD	7 1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 7; Liquid	Liquid	Vibrating tube method	6
POMD	7 1	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 7; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	6
POMD	7 1	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 7; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	6
POMD	4 1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 4; Liquid	Liquid	Vibrating tube method	6
POMD	4 1	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 4; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	6
POMD	4 1	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 4; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	6
POMD	6 1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 6; Liquid	Liquid	Vibrating tube method	6
POMD	6 1	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 6; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	6
POMD	6 1	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 6; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	6
POMD	5 1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 5; Liquid	Liquid	Vibrating tube method	6
POMD	5 1	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 5; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	6
POMD	5 1	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 5; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	6

Thermodynamics Research Center / ThermoML | Thermochimica Acta

Volumetric, compressibility and viscometric studies on sodium cholate/sodium deoxycholate amino acid interactions in aqueous medium

Kumar, K.[Kuldeep], Chauhan, S.[Suvarcha]

ABSTRACT