ABSTRACT

Solute solvent interaction of the mixtures containing dipeptides of glycine i.e. glycyl glycine and glycyl- L-leucine with aqueous solutions of antibacterial drug amoxicillin have been studied with the help of density and speeds of sound measurements at T = (305.15, 310.15, and 315.315) K. Apparent molar properties like apparent molar volume, apparent molar isentropic compression have been calculated from experimental data. Partial molar properties of transfer for dipeptides of glycine from water to aqueous amoxicillin solutions have been calculated from density and speeds of sound data. Limiting apparent molar isentropic compression, pair, and triplet interactions coefficients have also been calculated. The UV absorption studies have also been made in this study. The results have been discussed in terms of competing patterns of interactions prevailing in the solute and solvent.

Compounds

#	Formula	Name
1	C4H8N2O3	glycylglycine
2	C8H16N2O3	glycyl-L-leucine
3	C16H19N3O5S	amoxicillin
4	H2O	water

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	3
POMD	4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	3
POMD	1 4 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 3; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	132
POMD	1 4 3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 3; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	132
POMD	2 4 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 3; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	120
POMD	2 4 3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 3; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	120
POMD	1 4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	30
POMD	1 4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	30
POMD	4 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	9
POMD	4 3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	9
POMD	2 4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	27
POMD	2 4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	27

Thermodynamics Research Center / ThermoML | Thermochimica Acta

Volumetric, acoustic, and UV absorption studies on solute solvent interactions of dipeptides of glycine with aqueous amoxicillin solutions

Singla, M.[Meenu], Jindal, R.[Rajeev], Kumar, H.[Harsh]

ABSTRACT