ABSTRACT

Density and viscosity were measured for the binary mixtures of cefodizime sodium + water and theternary mixtures of cefodizime sodium + 0.9 mass % normal saline at the temperatures (278.15, 283.15,288.15, 293.15, 298.15, 303.15, 308.15, and 313.15) K and at atmospheric pressure. The dependenceof density and viscosity on temperature and concentration has been correlated with V T F equation. From the experimental data, apparent molar volumes, standard partial molar volumes, relativechanges in viscosity, and the viscosity B-coefficient of cefodizime sodium were calculated. The resultsare used to analyze the nature of solute solute. Using the Helper equation and the Jones Dole equation,solute solvent interactions and structure breaking effect of cefodizime sodium have been discussed. Theresults have been interpreted in terms of solute solvent and solute solute interactions and structuremaking/breaking ability of solute in the aqueous solution.

Compounds

#	Formula	Name
1	C20H18N6Na2O7S4	sodium (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((5-(carboxylatomethyl)-4-methylthiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
2	H2O	water
3	ClNa	sodium chloride

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	2	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	8
POMD	2	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	8
POMD	2 1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	72
POMD	2 1	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	72
POMD	3 2 1	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Solvent: Mass fraction - 3; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	72
POMD	3 2 1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Solvent: Mass fraction - 3; Liquid	Liquid	Vibrating tube method	72
POMD	3 2	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Mass fraction - 3; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	8
POMD	3 2	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Mass fraction - 3; Liquid	Liquid	Vibrating tube method	8

Thermodynamics Research Center / ThermoML | Thermochimica Acta

Densities and viscosities of cefodizime sodium in water and normalsaline from (278.15 to 313.15) K

Li, Y.[Yu], Li, Y.-H.[Yan-Hong], Wang, F.-a.[Fu-an], Ren, B.-z.[Bao-zeng]

ABSTRACT