Thermodynamics Research Center / ThermoML | Thermochimica Acta

Solubility of disodium cytidine 5'-monophosphate in different binarymixtures from 288.15 K to 313.15 K

Yu, J.[Jin], Ma, T.[Tianle], Li, A.[An], Chen, X.[Xiaochun], Chen, Y.[Yong], Xie, J.[Jingjing], Wu, J.[Jinglan], Ying, H.[Hanjie]
Thermochim. Acta 2013, 565, 1-7
ABSTRACT
The solubility of disodium cytidine 5 -monophosphate (5 -CMPNa2) in methanol + water andethanol + water binary mixtures was measured experimentally at the temperatures ranging from 288.15to 313.15 K. The results showed that the solubility of 5-CMPNa2 increased with the increasing of temper-ature and the mole fraction of water in different binary mixtures. The (CNIBS)/Redlich Kister model andthe semi-empirical Apelblat model were applied for the prediction of the experimental data. Both modelscould give satisfactory simulation results. In addition, the thermodynamic properties of the dissolutionprocess such as Gibbs energy, enthalpy, and entropy were calculated using the van t Hoff equation andthe Gibbs equation. The results indicated that the dissolution process was endothermic.
Compounds
# Formula Name
1 CH4O methanol
2 C9H12N3Na2O8P disodium cytidine 5'-monophosphate
3 H2O water
4 C2H6O ethanol
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • 3
  • Mole fraction - 2 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 1; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 2
  • Chromatography
  • 42
  • POMD
  • 4
  • 2
  • 3
  • Mole fraction - 2 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 4; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 2
  • Chromatography
  • 35