ABSTRACT

Enthalpies of solution of glycine, l-alanine and l-serine in aqueous solutions of N-methylacetamide and N,N-dimethylacetamide were measured at 298.15 K. Enthalpies of transfer ( trH) of amino acids from water to aqueous solutions of amides were derived. It has been show that the enthalpies of transfer of amino acids are positive and increase with the increasing concentration of amides. The relative order of trH of amino acids in the same concentration of NMA or DMA is l-serine less than glycine less than l-alanine. The influence of side group of l-alanine and l-serine on trH has been discussed in terms of structural interaction. The results were compared with those in aqueous formamide, N-methylformamide and N,N-dimethylformamide solutions.

Compounds

#	Formula	Name
1	C2H5NO2	2-aminoacetic acid
2	C3H7NO2	(S)-2-aminopropanoic acid
3	C3H7NO3	L-serine
4	C3H7NO	N-methylacetamide
5	C4H9NO	N,N-dimethylethanamide
6	H2O	water

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1 4 6	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 4; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Mole fraction - 1; Liquid	Liquid	Calvet calorimetry	9
POMD	2 4 6	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 4; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Mole fraction - 2; Liquid	Liquid	Calvet calorimetry	9
POMD	3 4 6	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 4; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Mole fraction - 3; Liquid	Liquid	Calvet calorimetry	9
POMD	1 5 6	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 5; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Mole fraction - 1; Liquid	Liquid	Calvet calorimetry	8
POMD	2 5 6	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 5; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Mole fraction - 2; Liquid	Liquid	Calvet calorimetry	8
POMD	3 5 6	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 5; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Mole fraction - 3; Liquid	Liquid	Calvet calorimetry	8

Thermodynamics Research Center / ThermoML | Thermochimica Acta

Enthalpies of transfer of amino acids from water to aqueous solutions of N-methylacetamide and N,N-dimethylacetamide at T=298.15K

Zhou, L.[Li], Liu, C.[Chunli]

ABSTRACT