ABSTRACT

Enthalpies of solution of glycine, l-alanine, l-serine in water and aqueous solutions of formamide were measured at 298.15 K. Transfer enthalpies of amino acids from water to aqueous solutions of formamide were derived and interpreted qualitatively with hydration co-sphere overlap model. The results show that the structure interaction between formamide and zwitterionic head-group and hydrophilic side chain of amino acids make a negative contribution to transfer enthalpy, while that with the hydrophobic side chain is positive. In the solvent composition range studied, transfer enthalpies decrease overall with the increasing concentration of formamide, with the relative order of l-serine < glycine < l-alanine.

Compounds

#	Formula	Name
1	C2H5NO2	2-aminoacetic acid
2	C3H7NO2	(S)-2-aminopropanoic acid
3	C3H7NO3	L-serine
4	H2O	water
5	CH3NO	formamide

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1 4	Molar enthalpy of solution, kJ/mol ; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Molality, mol/kg - 1; Liquid		Liquid	CALVET:solid	1
POMD	2 4	Molar enthalpy of solution, kJ/mol ; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Molality, mol/kg - 2; Liquid		Liquid	CALVET::solid	1
POMD	3 4	Molar enthalpy of solution, kJ/mol ; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid Molality, mol/kg - 3; Liquid		Liquid	CALVET::solid	1
POMD	1 5 4	Molar enthalpy of solution, kJ/mol ; Liquid	Molality, mol/kg - 1; Liquid Solvent: Molality, mol/kg - 5; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid	Liquid	CALVET:solid	9
POMD	2 5 4	Molar enthalpy of solution, kJ/mol ; Liquid	Molality, mol/kg - 2; Liquid Solvent: Molality, mol/kg - 5; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid	Liquid	CALVET:solid	9
POMD	3 5 4	Molar enthalpy of solution, kJ/mol ; Liquid	Molality, mol/kg - 3; Liquid Solvent: Molality, mol/kg - 5; Liquid	Temperature, K; Liquid Pressure, kPa; Liquid	Liquid	CALVET:solid	9

Thermodynamics Research Center / ThermoML | Thermochimica Acta

Enthalpies of transfer of amino acids from water to aqueous solutions of formamide

Ma, L.[Lin], Xu, N.[Nan], Lin, G.[Guimei], Lin, R.[Ruisen]

ABSTRACT