Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Volumetric approach to the interaction of L-Proline in aqueous Metformin Hydrochloride solutions for temperature range 298.15-318.15 K

Rajagopal, K., Roshan, M. Mohamed, Shailajha, S., Renold, G. Roy Richi
J. Chem. Thermodyn. 2019, 133, 312-319
ABSTRACT
Densities rho, have been measured for l-Proline in aqueous Metformin Hydrochloride solutions of (0.05, 0.10, 0.15 and 0.20 M) mol kg-1 at T = 298.15-318.15 K. Apparent molal volumes Vphi have been determined from the experimental densities. These data have been used to calculate several thermodynamical parameters such as standard partial molal volume Vphi0, transfer volume deltatrVphi0, hydration number nH, the second derivative of infinite dilution of partial molal volume with respect to temperature, viz., d2Vphi0/dT2. Furthermore apparent molar expansibility E0, thermal expansion coefficient, alpha2 and the pair and triplet interaction coefficient have been calculated and reported. These results interpreted through a co-sphere overlap model indicate the presence of strong solute-co-solute interactions in the reported systems.
Compounds
# Formula Name
1 C5H9NO2 L-proline
2 C4H12ClN5 N,N-dimethylimidodicarbonimidic diamide hydrochloride
3 H2O water
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 3
  • Mass density, kg/m3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Pycnometric method
  • 5
  • POMD
  • 1
  • 2
  • 3
  • Mass density, kg/m3 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Molality, mol/kg - 2; Liquid
  • Molality, mol/kg - 1; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Pycnometric method
  • 150
  • POMD
  • 2
  • 3
  • Mass density, kg/m3 ; Liquid
  • Temperature, K; Liquid
  • Molality, mol/kg - 2; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Pycnometric method
  • 25
  • POMD
  • 1
  • 3
  • Mass density, kg/m3 ; Liquid
  • Temperature, K; Liquid
  • Molality, mol/kg - 1; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Pycnometric method
  • 30